|
rs2278420
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ZNF350 L66P variant modifies the risk of breast cancer not only by itself but also in a gene-environment interaction manner with age, age at menarche, menopause status, or estrogen receptor status.
|
29653063 |
2018 |
|
rs80357275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ZNF350 L66P variant modifies the risk of breast cancer not only by itself but also in a gene-environment interaction manner with age, age at menarche, menopause status, or estrogen receptor status.
|
29653063 |
2018 |
|
rs56012641
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Y179C, F486L and N550H are BRCA1 variants that may be associated with breast cancer in a Sicilian family: results of a 5-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
|
16760288 |
2006 |
|
rs55906931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Y179C, F486L and N550H are BRCA1 variants that may be associated with breast cancer in a Sicilian family: results of a 5-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
|
16760288 |
2006 |
|
rs80357400
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Y179C, F486L and N550H are BRCA1 variants that may be associated with breast cancer in a Sicilian family: results of a 5-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
|
16760288 |
2006 |
|
rs861539
|
|
|
0.100 |
GeneticVariation |
BEFREE |
XRCC3 codon 241 Thr/Met or Met/Met genotype moderately increased the risk of breast cancer (OR = 1.4, 95% CI: 0.87-2.33), but not significant in this study.
|
17063279 |
2007 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
XRCC1 Arg399Gln and Arg164Trp variant genotypes are associated with an increased risk of BC in Egyptian females.
|
25340946 |
2014 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
XRCC1 R399Q was not associated with breast cancer (O.R.1.00, 95% C.I.0.61-1.64).
|
16596326 |
2006 |
|
rs1047768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
XPG rs1047768 was significantly associated with decreased PFS (HR 1.72; 95% CI 1.0-2.8) in breast cancer cases (P = 0.013) which was demonstrated by median time of 26 months for T > C variant when compared with median time of 37 months for TT genotype.
|
30255276 |
2018 |
|
rs1800975
|
|
|
0.040 |
GeneticVariation |
BEFREE |
XPA rs1800975 polymorphism may decrease the risk of breast cancer in both non-Asians and population-based patients.
|
29953005 |
2018 |
|
rs4756146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Women with ≥1 variant allele in CAT rs4756146 had a 23 % reduced risk of postmenopausal breast cancer compared with women with the common TT genotype (OR = 0.77; 95 % CI = 0.59-0.99).
|
23053794 |
2012 |
|
rs1695
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Women homozygous with the T allele in CYP1B1*2 (Ser(119); rs1056827) were at 1.69 (95% confidence interval, 1.17-2.46) times the risk of women homozygous with the G allele; women homozygous with the G allele in GSTP1 (Val(105); rs1695) were at 0.73 (95% confidence interval, 0.54-0.99) times the risk of breast cancer compared with women homozygous with the A allele.
|
19383894 |
2009 |
|
rs1056827
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Women homozygous with the T allele in CYP1B1*2 (Ser(119); rs1056827) were at 1.69 (95% confidence interval, 1.17-2.46) times the risk of women homozygous with the G allele; women homozygous with the G allele in GSTP1 (Val(105); rs1695) were at 0.73 (95% confidence interval, 0.54-0.99) times the risk of breast cancer compared with women homozygous with the A allele.
|
19383894 |
2009 |
|
rs2214102
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Women homozygous for the major ABCB1_rs2214102_G allele were found to be at a significantly increased breast cancer risk associated with combined estrogen-progestagen therapy [odds ratio (OR) = 1.17, 95% confidence interval (CI) = 1.12-1.23, P (interaction) = 0.022].
|
19672706 |
2010 |
|
rs16942
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Women carrying the rare allele of single nucleotide polymorphism rs16942 on the wild-type copy of BRCA1 were at decreased risk of breast cancer (hazard ratio 0.86, 95% confidence interval 0.77-0.95, P = 0.003).
|
21890493 |
2011 |
|
rs1800056
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Within the BC lines studied, the group composed of the six carrying the linked 2572T>C (858F>L) and 3161C>G (1054P>R) variants had a higher level of MN after IR exposure compared to that observed in the remaining four BC or in the normal cell lines.
|
15101044 |
2004 |
|
rs1800057
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Within the BC lines studied, the group composed of the six carrying the linked 2572T>C (858F>L) and 3161C>G (1054P>R) variants had a higher level of MN after IR exposure compared to that observed in the remaining four BC or in the normal cell lines.
|
15101044 |
2004 |
|
rs762551
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Within a hospital-based case-control study, the effect of functional CYP1A2 variants [-3860G/A (rs2069514), -2467T/delT (rs3569413), -163C/A (rs762551)] and their interactions with environmental factors in BC risk was investigated.
|
23128882 |
2013 |
|
rs2069514
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Within a hospital-based case-control study, the effect of functional CYP1A2 variants [-3860G/A (rs2069514), -2467T/delT (rs3569413), -163C/A (rs762551)] and their interactions with environmental factors in BC risk was investigated.
|
23128882 |
2013 |
|
rs3803662
|
|
|
0.800 |
GeneticVariation |
BEFREE |
With the exception of rs3803662 (TOX3), there was no evidence that any of the SNPs associated with BC susceptibility were associated with the BC survival.
|
22532573 |
2012 |
|
rs1130409
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With respect to APE1 Asp148Glu polymorphism, no significant association with breast cancer risk was demonstrated in the overall and stratified analyses.
|
24893568 |
2014 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With respect to A1298C polymorphism, no significant association with breast cancer risk was demonstrated in overall, ethnicity- and menopausal status-based population.
|
20135343 |
2010 |
|
rs67068737
|
|
|
0.010 |
GeneticVariation |
BEFREE |
With genetic changes in the syndecans and their association with breast cancers plausible, we examined two single nucleotide polymorphisms in SDC1 (rs1131351) and SDC4 (rs67068737) within an Australian Caucasian breast cancer case/control population.
|
25361632 |
2015 |
|
rs1057519365
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
rs1555460533
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene.
|
27648926 |
2017 |